Preventing a Catastrophe: Increasing Awareness of Loeys-Dietz Syndrome

Bradley S. Kane, MD; Kamran Shamsa, MD

Tex Heart Inst J (2019) 46 (1): 41–43.

Loeys-Dietz syndrome is a genetic disorder that predisposes patients to aortic aneurysms. If left untreated, the natural history of the associated aortopathy often culminates in fatal aortic dissection. We describe the case of a 21-year-old man who was diagnosed with Loeys-Dietz syndrome after 2 family members died of aortic dissection. This case highlights the importance of increased physician awareness of this syndrome, which can play a crucial role in preventing premature sudden cardiac death caused by aortic catastrophe.

Kane, Bradley S., and Kamran Shamsa. “Preventing a Catastrophe: Increasing Awareness of Loeys-Dietz Syndrome.” Texas Heart Institute Journal, vol. 46, no. 1, 1 Feb. 2019, pp. 41–43, https://doi.org/10.14503/thij-17-6387.

Accessed 14 Nov. 2020.

ResearchStacey WatsonAneurysm, Aortic Dissection, Genetics, Aortic Aneurysm, Thoracic Aortic Aneurysm, Practice Guidelines, Receptors, Growth Factor Beta